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UDC: 577.323.22 + 577.112.382.2 + 621.78.063            https://doi.org/10.62965/tnu.sns.2024.1.15

 

Eshova Gulrukhsor Bobonazarovna

Tajik National University

 

The processes of glycine ionization (Gly) have been studied by potentiometry and the values of pKa1 and pKa2 at 288.15 K, the ionic strength of the solution (Na(H)CIO4) have been calculated) 0.1, 0.25, 0.5, 0.75, 1.0 mol/l and concentrations 1.0÷3.0 · 10-3 mol/l with a confidence probability of P = 0.95.

With an increase in ionic strength and temperature, the pK of both amino and carboxyl groups and functional groups of the side radical decreases, which indicates an increase in the degree of their ionization and is consistent with the theory of weak electrolytes.

 

Keywords: Potentiometry, glycine, concentration, ionization constants, ionic strength, pH, zwitter ion.

 

Information about the author

 

Eshova Chaykhana Bobonazarovna- Tajik National University,

Candidate of Chemical Sciences, senior researcher of the Scientific Research Institute.

Address 734025, Dushanbe, Republic of Tajikistan, 17 Rudaki Avenue.

Phone: (+992) 918-23-01-82.

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

REVIEWER: Mabatkadamzoda K.S., Doctor of Chemical Sciences

 

REFERENCES

 

  1. Traven, V. F. Organic chemistry / V. F. Traven // M. Binom. 2013. - Vol. 3. - P. 388.
  2. Yakubke, H.D. Amino Acids / H.D. Jakubke, H. Eshkait // Peptides. Belki. M.: Mir, 1985. – P. 456.
  3. Syrovaya, A.O. Amino acids through the eyes of chemists, pharmacists, biologists: in 2 volumes, Vol. 1. H.: / A.O. Syrovaya, L.G. Shapoval, V.A. Makarov and others // Shchedra sadiba plus, 2014. – P. 228.
  4. Abdelkarim, A.T. Potentiometric, thermodynamics and coordination properties for binary and mixed ligand complexes of copper(II) with cephradine antibiotic and some N- and O-bound amino acids (α-alanine and β-alanine) / T. Abdelkarim, W. H. Mahmoud, A.A. & El-Sherif // Journal of Molecular Liquids, 2021. V. 328. – Pp.115334.
  5. Yusupov, Z.N. The influence of ionic strength on the values of the ionization constant of aminoethanic acid / Z.N. Yusupov, G.B. Eshova, S.S. Saidov // Doc. AN RT. - 2008. - vol. 51. - No. 8. – Pp.620-625.
  6. Popova, E.A. Synthesis and biological properties of amino acids and peptides containing a tetrazolyl fragment / E.A. Popova, R.E. Trifonov // Zhur. The successes of chemistry. - 2015. - vol. 84. - No. 9. – Pp.
  7. Eshova, B. Constants of Ionization of L-Alanine at Different Ionic Strengths of a Solution and Concentrations of Amino Acid / G.B. Eshova, Dzh.A. Davlatshoeva, M. Rakhimova, F. Miraminzoda, M. A.Toirzoda // Russian Journal of Physical Chemistry A, 2023, Vol. 97, No. 10.  – Pp.2144–2148 DOI: 10.1134/S0036024423100084
  8. Khokhlov, V.Yu. Ionic equilibria in solutions of amino acids at different temperatures / V.Yu. Khokhlov, V.F. Selemenev, O.N. Khokhlova, A.A. Zagorodny // West. VSU. Series chemistry, biology, pharmacy. - 2003. - No. 1. – Pp.18-22.
  9. Samadov, A.S. The effect of temperature on the acid-base properties of β-alanine in an aqueous solution / S. Samadov, J.N. Khakimov, A.F. Stepnova, E.F. Fayzullozoda, A.V. Kuzin // Russian Journal of Physical Chemistry A, 2023, - Vol. 97, No. 4.  – Pp.512-516. DOI: 10.31857/S004445372304026X
  10. Suslennikova, V.M. Guidelines for the preparation of titrated solutions / V.M. Suslennikova, E.K. Kiseleva // L.: Khimiya, 1968. – P.144.
  11. Charlot, G. Methods of analytical chemistry. Quantitative analysis of inorganic compounds / G. Charlot // trans. from French. Yu. Lurie. M.: Chemistry, 1965. - P. 930.
  12. Albert, A. Constants of ionization of acids and bases / A. Albert, E. Sergeant // Trans. from English – M.- L.: Chemistry, 1964. - 177 p.
  13. N. Zaidel // Ed. 3rd, Spanish and additional - L.: Nauka, 1968. – P. 96.
  14. Walkenbach, D. Formulas in Excel 2013. / D. Walkenbach // M.: Dialectics, 2019. - 720 P.
  15. Dawson, R. Handbook of Biochemistry: Translated from English / R. Dawson, D. Elliot, W. Elliot, K. Jones – M.: Mir, 1991. - P. 544.
  16. Zapadnyuk, V. I. Amino acids in medicine. – Kiev: / V. I. Zapadnyuk, L. P. Kuprash, M. U. Zaika, I. S. Bezverkhaya // Health, 1982. – P. 200.
  17. Harner, G. Physical chemistry of electrolyte solutions / Edited by A.F. Kapustinsky. / G. Harner, B. Owen // - M.: Gosinoizdat, 1952. – P. 628.

 

 

Article received: 06.12.2023

Approved after review: 08.01.2024

Accepted for publication: 27.02.2024

   
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